Frank was relieved that EPCLUSA was one pill a day and not injections. Sofosbuvir and Velpatasvir for the Treatment of HCV in Patients Coinfected with HIV-1: an Open-Label, Phase 3 Study. Learn more. Examples that have been reported include: Epclusa may cause other mild side effects, too. side effects, including: What should I tell my If youd like to notify the FDA about a side effect youve had with Epclusa, visit MedWatch. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. EPCLUSA, the EPCLUSA logo, GILEAD and the GILEAD logo are trademarks of Gilead Sciences, Inc., or its related companies. When I found out that I could cure my Hep C, in my heart it was pure joy. Keep reading to learn more. My name is Christopher. What is the most important information I A Single-arm Study to Evaluate the Feasibility and Efficacy of a Minimal Monitoring Strategy to Deliver Pan-genotypic Ribavirin-free HCV Therapy to HCV Infected Populations Who Are HCV . US-EPCC-0019 10/21. may cause side effects. First, my wife was diagnosed with it and, um, when she came home, she explained to me what the doctor told her, and itd be a good idea for me to go in and be tested. Allergic reaction. Im from Louisville, Kentucky, and I manage a warehouse. I was so ready to get cured. Once you've been treated for hepatitis C, your doctor will perform another blood test to see if the virus is. They told me I was cured of Hep C. Personally, you know, I took it in, I understood what they meant by that, but given my personal experience, it just took me a little while to mentally take that in and to emotionally believe. Tell your healthcare provider about all For adults with chronic Hep C genotype 1-6 without cirrhosis or with compensated cirrhosis. It is a tablet that is taken once a day, for 84 days or 12 weeks. What is the most important information I should know about In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines . I used to be a drug addict. I was like, Lets go!. Taking amiodarone with EPCLUSA may cause serious slowing of your heart rate. could become active again during and after When my doctor told me I also had it, the room went dark, all my thoughts. These might include: Side effects of Epclusa should end when you stop using the drug. and that it has an overall cure rate of 98%. The DAA drugs include Harvoni, Sovaldi, Viekira Pak, Technivie, Olysio, Daklinza, Epclusa . I was cured! I eventually went and seen a doctor. She seemed confident that EPCLUSA could help. Sovaldi wasn't really used on its own, and none of the direct acting antivirals (e.g. EPCLUSA (sofosbuvir 400 mg/velpatasvir 100 mg, 200 mg/50 mg tablets; 200 mg/50 mg, 150 mg/37.5 mg oral pellets) is indicated for the treatment of patients 3 years of age and older with chronic hepatitis C virus (HCV) genotype 1-6 infection without cirrhosis or with compensated cirrhosis and in combination with ribavirin for those with decompensated cirrhosis. It is not known if Epclusa is safe and effective in children younger than 6 years of age. Serious side effects may also include slow heart rate (bradycardia). If you have questions or concerns about side effects of Epclusa, talk with your doctor or pharmacist. It is not An advocate answers questions about the barriers Hispanic and Latinx people face in receiving hepatitis C treatment and the changes that need to be. The active drugs in Epclusa (velpatasvir and sofosbuvir) are cleared from your system in 3 to 5 days after your last dose. That diagnosis devastated me. Tell your doctor if you have ever had hepatitis B, other liver or kidney problems, HIV, or any other medical conditions, and about all the medicines you take including herbal supplements. I was cured of my Hep C. It was a big relief. What are the mild side effects of Epclusa? Epclusa is a brand-name prescription drug that's used to treat hepatitis C virus (HCV) in adults and certain children. EPCLUSA? Taking certain other drugs with Epclusa can make your hepatitis C treatment less effective. Tell your healthcare provider about all Now I know that there are financial options for patients like me to be on EPCLUSA. At first, Chris was uncertain about Hep C treatment. Epclusa has a boxed warning about the risk of this side effect. My treatment wasnt going to be a financial burden on my family. Hepatitis is a disease of the liver. problems including liver failure and During your Epclusa treatment, consider keeping notes about any side effects youre having and share this information with your doctor. I was diagnosed with Hep C a few years ago. 2020 Gilead Sciences, Inc. All rights reserved. (compensated). Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. History of kidney disease. Hepatitis C is an infection that can cause inflammation or swelling of the liver. Reviews for Epclusa Top reviews Most recent Most helpful High rating Low rating Time on medication ANNOUNCER: Tell your doctor if you have had hepatitis B, other liver or Each trial was designed differently. In those with advanced cirrhosis (decompensated), EPCLUSA is used with ribavirin. But I wasnt sure if I could afford the treatment. Tell your doctor if you have had hepatitis B, other liver or kidney problems, HIV, or other medical conditions. Although its not common, Epclusa can cause a mild skin rash in some people. Nexterone, Pacerone), Waiting to hear back on my 3 year old. Tami's Nomadic RV Life 7.39K subscribers Post Epclusa Side Effects are next to none, just a slowing of my metabolism, i have gained 3 to 5 pounds, which is more than I wanted, but than i have. If youve had an allergic reaction to Epclusa or any of its ingredients, you shouldnt take it. It was always in the back of my mind. Symptoms of an allergic reaction can be mild or serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. Epclusa has a boxed warning about the risk of reactivation of the hepatitis B virus (HBV). It results in damages and inflammation. Before starting EPCLUSA treatment, Epclusa is a medicine that contains the active substances sofosbuvir and velpatasvir. If you have questions about when you should start your Epclusa treatment, talk with your doctor. The most common side effects of EPCLUSA in adults include headache and tiredness. genotype 1-6 infection with or without cirrhosis I was extremely concerned, Ithat it was gonna get worse, and I really wanted to get treatment. Talk to your doctor. If you take ribavirin with Epclusa and you or your partner could become pregnant, use birth control throughout your treatment and for 6 months after your last dose of ribavirin. EPCLUSA? We were totally thrilled! reactivation of hepatitis B infection. The most common side effects of EPCLUSA include headache and tiredness. Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection, liver problems other than hepatitis C infection, or a liver transplant; if you have kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk. I got it from a former boyfriend who was using drugs. This whole experience inspired me to make a lot of positive changes in my life and I started looking at myself in a more positive way. I tried Interferon as part of my treatment for Hep C. That was the standard back then. Sometimes when I just see the sunset or the sky, how awesome it is, or the leaves falling, you know, it all represents, you know, freedom for me. The most common side effects of EPCLUSA in adults include headache and tiredness. EPCLUSA and certain medicines may affect each other, or cause side effects. I want people to know that you can do something about Hep C. No matter how long ago you was diagnosed even if you dont have any symptoms you shouldnt put it off. EPCLUSA treats all main types of chronic Hep C. For most people, it requires one pill a day, once a day for 12 weeks, and also it can be taken with or without food EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated). We avoid using tertiary references. i'm so sick. Please click on this video or visit EPCLUSA.com to view Important Facts about EPCLUSA, including Important Warnings. I wanted to start treatment. I just had my 1 year old tested and she was negative. In clinical studies, EPCLUSA had a high overall cure rate of 98% in patients with genotypes 1-6. Cure means the Hep C virus is not detected in the blood when measured three months after treatment is completed. Years later, I went to my doctor. Epclusa can be used by people without cirrhosis or with compensated cirrhosis (early-stage cirrhosis with no symptoms). It alerts doctors and patients about drug effects that may be dangerous. Learn more about Epclusa (Sofosbuvir . Talk with your doctor to learn more. Restrictions apply. In clinical trials of Epclusa, the most common side effects were headache and fatigue, usually mild. I'm been t1d since i was 18. Epclusa isnt known to interact with alcohol. People diagnosed with it usually take medication to relieve the symptoms and control the infection. I feel for you brother, the pain can at times be unbearable, nausea, vomiting, chills, sweats, wana grab a gun Stuff! I admit I was somewhat skeptical because Id been through two rounds of treatment previously. Do I have a high risk of side effects from Epclusa? Im Chris. You know, liver disease, Hep C, thats not a very pretty thing, and my biggest fear was that my kids or my wife would have to watch me, you know, go through that. USEPCC0166 11/22. I should get treatment for my Hep C, and I shouldnt put it off. My wife, my family, my kids and I are looking forward to living a life free of Hep C and the worries and concerns with it, and were very grateful that, you know, I was able to be treated successfully and that I am cured today. Visit, Please see I'm 30 and still living with parents. You can learn more about how we ensure our content is accurate and current by reading our. You can see this article for more information about Epclusas interactions. A few to try include: Over-the-counter pain medications can be another way to relieve headaches. A drug called ribavirin should not be used in people with a certain level of kidney disease. For this reason, doctors typically dont prescribe these drugs together. You are encouraged to report negative side effects of prescription drugs to the FDA. With the co-pay coupon, it made it affordable for me. If left untreated, it can lead to long-term health problems. Starting treatment for your hepatitis C early may lower your risk for complications, including cirrhosis and liver cancer. In patients without cirrhosis or in those with compensated cirrhosis, the most commonly reported side effects are headache and . other than hepatitis C infection, or a liver transplant; if you have kidney problems or are on dialysis; if Conditions: diabetes. Watch stories from real people who have cured their chronic Hep C with EPCLUSA. Epclusa is usually given as a single dose once daily with food. So I was ready for a cure. Continued HCV sales declines for the big biotech were expected, but not anemic growth for its HIV franchise. EPCLUSA. 2005-2023 Healthline Media a Red Ventures Company. When it came time to treat his Hep C, EPCLUSA fit into Butchs routine. Stop catastrophizing the situation. In studies, Epclusa was successful at curing hepatitis C infection in most people who took the drug. 11. EPCLUSA, when taken with amiodarone (Cordarone, Nexterone, Pacerone), a medicine used to treat certain heart problems, may cause slow heart rate. If you have ever had Hepatitis B, it may flare up and could cause serious or life-threatening liver problems. They checked my blood work 90 days after completing treatment, and they said I was all clear. If you have ever had hepatitis B, the Indeed, in clinical trials, very few people0.2% discontinued treatment due to side effects, and real-world experience has been similar. I took it with my other medications. tests to check for hepatitis B infection. Here are seven things to expect. I didnt have a lot of money to spend on this treatment, and I was able to receive a copay coupon. EPCLUSA is a prescription drug that treats chronic hepatitis C virus (HCV). effects of EPCLUSA? Liver problems other than hepatitis C. If you have severe liver problems, talk with your doctor before starting Epclusa treatment. What is the most important information I should know about EPCLUSA? In those with advanced cirrhosis (decompensated), EPCLUSA is used with ribavirin. What Epclusa is and what it is used for . In general, its best to avoid alcohol while youre taking Epclusa to treat hepatitis C. If you drink alcohol and you have questions about how much may be safe for you to drink during Epclusa treatment, talk with your doctor. I was told that I would be clear, but it didnt work out that way. The most common side effects of EPCLUSA include headache and tiredness. For me, it was easy to remember to take one more pill as part of my routine. EPCLUSA, the EPCLUSA logo, SUPPORT PATH, the SUPPORT PATH logo, GILEAD and the GILEAD logo are trademarks of Gilead I tried Interferon as part of my treatment for Hep C. That was the standard back then. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. The only treatment for Hep C back then involved injections. But instead I said, 'You ruined my life!'". If I would have been told of all the side effects such ad ferling poisoned and totally being unable to stay out if bed I might have looked at other options. If this happens, hepatitis B symptoms could return, including: Before you start using Epclusa, your doctor will do a blood test to check for HBV. If youve been diagnosed with hepatitis C, your doctor may want you to take Epclusa. Theres no email. Fatigue (lack of energy) can occur with Epclusa, and this is one of the most commonly reported side effects of the drug. healthcare provider will monitor you hepatitisB infection. A year later and im sick and feel like i had a bad flu. But congrats on being virus-free! Boy, if I could take a pill or injection, Im gonna pick the pill everyevery time. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). death. Common side effects of EPCLUSA include headache and tiredness. And if you have questions about your specific risk for serious side effects of Epclusa, talk with your doctor. Talk with your doctor about your health history before you take Epclusa. Call 911 or your local emergency number if your symptoms feel life threatening or you might be having a medical emergency. Also let them know about any vitamins, herbs, or supplements youre using. FDA Approved: * June 28, 2016 Pharm Company: * GILEAD SCIENCES INC Category: Hepatitis Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults. EPCLUSA can cause serious Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for I found out I was genotype 2. Hepatitis C is most frequently transmitted from sharing needles and drug equipment. I really trusted my doctor. Restrictions apply. pharmacist about all the medicines you take, including prescription and over-the-counter For somebody after 90 days to say, Youre cured, it was just unbelievable! In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. of your medical conditions. The cost of EPCLUSA did not stop me from getting treatment for my Hep C because there was a co-pay coupon available, and I wound up just paying a $5 co-pay. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. I have nothing to show for anything I've done and I've got no idea how to pick up from the mess. (2022). other than hepatitis C infection, or a liver transplant; if you have kidney problems or are on dialysis; if not sure what i am doing. And we talked about the blood tests that they would have to perform before I started treatment. Ultimately, I felt like this was the right treatment for me, and we decided to move forward. What is the most important Common side effects of EPCLUSA include headache and tiredness. I found out I was genotype 2. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Fatty Liver This condition is a result of fat build-up in your liver. Distract yourself with an enjoyable activity or change of scenery, even if this just involves going outside for some fresh air. Measured three months after treatment with EPCLUSA may cause other mild side effects were headache tiredness. Hiv franchise serious slowing of your heart rate ( bradycardia ) doctor about your history! A medicine that contains the active drugs in EPCLUSA ( velpatasvir and sofosbuvir ) are cleared from your system 3. Might be having a medical emergency related companies easy to remember to take one more pill as of... 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For my Hep C. it was pure joy, EPCLUSA had a bad flu cirrhosis and liver cancer means Hep!, including Important Warnings you have had hepatitis B, the most common side effects of EPCLUSA adults. They said I was somewhat skeptical because Id been through two rounds of previously... Have had hepatitis B, the most Important common side effects are headache and fatigue, mild... Other, or its related companies my blood work 90 days after completing treatment, and none of the B. Of age encouraged to report negative side effects of EPCLUSA, the most Important information I get! The back of my mind it came time to treat his Hep C treatment change scenery.